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. 2017 Dec 1;10(12):11828–11837.

Figure 5.

Figure 5

The mechanism of miR-30b targeted CBX3 in activating JAK2/STAT3 pathway, thus regulating ESCC cell proliferation, apoptosis, and migration. A. The Western blot showing the protein expression of p-JAK2/JAK2, p-STAT3/JAK3, and p-STAT5/STAT5 in TE-1 cells transfected with miR-30b mimic, mimic control, miR-30b mimic plus blank control, and miR-30b mimic plus pc-CBX3. B. The regulatory mechanism. Red nodes indicate upregulation while blue nodes indicate downregulation. **P<0.01 and ***P<0.001 compared with corresponding control.