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. 2019 Dec 27;19(2):1472–1478. doi: 10.3892/etm.2019.8374

Table I.

Characteristics of trials included in the meta-analysis of garlic on blood pressure in hypertensives (SBP ≥140 mmHg, DBP ≥90 mmHg at baseline).

Author/(Refs.), year No. of subjects (garlic/control group) Garlic type Brand Country of manufacture Dosage (mg/day) Dosage of active ingredient per day Duration (weeks) Garlic Baseline mean SBP/DBP (mmHg) Control Baseline mean SBP/DBP (mmHg)
Kandziora et al (28), 1988 20/20 GP Kwai Germany 600 7.8 mg alliin 12 174/99 175/98
Auer et al (29), 1990 24/23 GP Kwai Germany 600 7.8 mg alliin 12 171/102 161/97
Vorberg and Schneider (30), 1990 20/20 GP Kwai Germany 900 11.7 mg alliin 16 144.5/91 144/88
Holzgartner et al (31), 1992 47/47 GP Kwai Germany 900 11.7 mg alliin 12 143/83 141/82
Santos and Gruenwald (32), 1993 25/27 GP Kwai Germany 900 11.7 mg alliin 24 143/89 144/89
Sobenin et al (33), 2008 23/19 GP Allicor Russia 600 7.8 mg allicin pt 12 143/89 140/88
Sobenin et al (34), 2009 G2: 18/20 GP Allicor Russia 2400 31.2 mg allicin 8 153/95 150/94
Ried et al (5), 2010 HT: 6/10 AGE Kyolic High Potency USA for Australia/NZ 960 (4 caps) 2.4 mg SAC 12 135/74 141/76
Ried et al (6), 2013 G2: 20/17 AGE Kyolic High Potency USA for Australia/NZ 480 (2 caps) 1.2 mg SAC 12 149/76 149/76
Nakasone et al (35), 2013 HT: 23/24 GPjpn Dentou ninniku ranwo™ Japan 188 NR 12 HT: 142/91 HT: 142/92
Ried et al (7), 2016 HT: 38/26 AGE Kyolic Reserve USA 1200 (2 caps) 1.2 mg SAC 12 HT: 154/96 HT: 146/93
Ried et al (8), 2018 23/26 AGE Kyolic Reserve USA 1200 (2 caps) 1.2 mg SAC 12 153/93 144/90

AGE, aged garlic extract; GP, garlic powder; GPjpn, Japanese garlic powder containing egg yolk; G2, main garlic group, P, placebo group; HT, hypertensive subgroup; RG, raw garlic; mg; milligram; mg/dl, milligram per decilitre; mmHg, millimetre of mercury; NA, not applicable; NR, not reported; NZ, New Zealand; pt, potential; SAC, S-allylcysteine; SBP/DBP, systolic/diastolic blood pressure.