Table 3.
Clinical, hormonal, and biochemical characteristics of overweight/obese and normal-weight patients with PCOS.
| PCOS (BMI ≥ 25 kg/m2) N = 75 | PCOS (BMI < 25 kg/m2) N = 48 | P-value | |
|---|---|---|---|
| Age (year) | 29.56 ± 3.10 | 30.52 ± 2.95 | 0.090 |
| BMI (kg/m2) | 28.90 ± 2.95 | 21.87 ± 3.47 | 0.000 |
| Testosterone (ng/ml) | 0.77 ± 0.34 | 0.65 ± 0.17 | 0.008 |
| Estradiol (pg/ml) | 65.69 ± 63.57 | 70.35 ± 44.07 | 0.658 |
| LH (mIU/ml) | 10.23 ± 5.60 | 12.92 ± 6.15 | 0.013 |
| FSH (mIU/ml) | 6.65 ± 2.04 | 7.01 ± 2.01 | 0.332 |
| LH/FSH ratio | 1.58 ± 0.80 | 1.90 ± 0.92 | 0.049 |
| Prolactin (ng/ml) | 11.82 ± 12.01 | 10.15 ± 5.32 | 0.366 |
| Progesterone (ng/ml) | 0.73 ± 1.26 | 1.27 ± 3.54 | 0.316 |
| AMH (ng/ml) | 7.66 ± 4.24 | 9.60 ± 4.95 | 0.022 |
| AST (U/L) | 22.96 ± 10.34 | 16.79 ± 5.89 | 0.000 |
| ALT (U/L) | 32.16 ± 22.12 | 18.56 ± 12.53 | 0.000 |
| GGT (U/L) | 30.69 ± 18.11 | 19.00 ± 11.13 | 0.000 |
| ALP (U/L) | 77.75 ± 16.99 | 73.23 ± 16.04 | 0.143 |
| Total cholesterol (mmol/L) | 4.89 ± 0.87 | 4.76 ± 0.81 | 0.392 |
| Triglyceride (mmol/L) | 1.87 ± 1.18 | 1.27 ± 0.70 | 0.002 |
| HDL-C (mmol/L) | 1.07 ± 0.27 | 1.41 ± 0.36 | 0.000 |
| LDL-C (mmol/L) | 3.12 ± 0.74 | 2.88 ± 0.66 | 0.069 |
| ApoA1 (g/L) | 1.38 ± 0.21 | 1.60 ± 0.27 | 0.000 |
| ApoB (g/L) | 0.95 ± 0.24 | 0.81 ± 0.18 | 0.001 |
| Fasting insulin (mU/L) | 19.52 ± 7.98 | 12.58 ± 6.63 | 0.000 |
| Fasting glucose (mmol/L) | 5.33 ± 0.61 | 5.01 ± 0.51 | 0.003 |
| HOMA-IR | 4.68 ± 2.11 | 2.87 ± 1.84 | 0.000 |
| No. of oocytes retrieved | 16.77 ± 6.84 | 20.69 ± 8.65 | 0.010 |
| No. of cleavage embryos | 11.60 ± 6.11 | 14.50 ± 8.01 | 0.035 |
| No. of good-quality embryos on day 3 | 5.55 ± 5.24 | 6.10 ± 4.94 | 0.557 |
Data was presented as mean ± standard deviation (SD). BMI, body mass index; LH, luteinizing hormone; FSH, follicle-stimulating hormone; AMH, anti-Müllerian hormone; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyltransferase; ALP, alkaline phosphatase; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B.