. 2019 Dec 11;19(2):1175–1182. doi: 10.3892/etm.2019.8315

Table II.

mRNA expression levels of cytokines and transcription factors in splenocytes isolated from OVA-immunized mice.

Gene	OVA	OVA + alum	OVA + 50 µg RCIE	OVA + 100 µg RCIE	OVA + 200 µg RCIE
IL-2	1.01±0.12	1.27±0.34	1.07±0.32	1.99±0.39^a	1.65±0.29^a
IFN-γ	1.01±0.13	1.08±0.32	2.25±0.37^b	2.32±0.39^b	1.63±0.63^a
T-bet	1.00±0.08	1.19±0.12	2.13±0.52^a	2.28±0.63^a	1.26±0.32
IL-4	1.02±0.22	4.07±1.32^b	2.33±0.60^a	2.49±0.18^a	1.51±0.12
IL-10	1.01±0.17	3.07±1.02^a	1.70±0.77	4.93±1.49^b	4.53±1.88^b
GATA-3	1.02±0.21	5.32±1.16^b	1.24±0.44	2.19±0.62^a	1.40±0.26

Values are presented as mean ± SEM (n=10).

P<0.05

P<0.01 vs. OVA. IL, interleukin; IFN-γ, interferon-γ; TNF-α; tumor necrosis factor-α; alum, aluminum hydroxide gel; RCIE, red clover isoflavone extract; OVA, ovalbumin.