Table 3.

Normalized content of nAChR subunits in the mitochondria of the mice listed in Table 1.

Groups/nAChR subunits	α3	α4	α7	α9	β2	β4
Ctrl	100 ± 1	100 ± 6	100 ± 1	100 ± 9	100 ± 3	100 ± 18
LPS	120 ± 9*	92 ± 5	108 ± 3	114 ± 12	116 ± 6	169 ± 40*
LPS+PNU282	200 ± 14###	110 ± 8##	143 ± 17###	154 ± 25#	146 ± 22#	171 ± 9
LPS+PNU120	113 ± 7	119 ± 8###	135 ± 8#	147 ± 9###	103 ± 7	191 ± 9
LPS+PNU120/282	121 ± 11	106 ± 5###	112 ± 3	159 ± 22##	122 ± 5	165 ± 7
LPS+Nic	146 ± 16#	75 ± 11#	118 ± 5#	137 ± 20	124 ± 18	135 ± 5
LPS 2m	153 ± 8**	77 ± 7*	86 ± 7*	157 ± 12*	115 ± 8	163 ± 14*
LPS 2m+PNU282	161 ± 4	88 ± 10	119 ± 17&	148 ± 29	123 ± 3	187 ± 15

Data are shown as Mean ± SD, the data of non-treated mice (Ctrl) being taken as 100%. *p < 0.05; **p < 0.005 compared to Ctrl; ^#p < 0.05; ^##p < 0.005; ^###p < 0.0005 compared to LPS 14d; and ^&p < 0.05 compared to LPS 2m; n = 5. The row LPS+PNU282 combines data obtained for groups 3 and 4 (Table 1: PNU282 given either simultaneously with or 7 days after LPS). Significantly changed values are marked in Bold (in the electron version, red marks increase, blue marks decrease).