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. 2019 Dec 5;19(2):999–1005. doi: 10.3892/etm.2019.8294

Figure 5.

Figure 5.

LINC00858 knockdown inhibits proliferation, migration and invasion of RB cells by promoting miR-3182. (A) SO-RB50 and Y79 cells of the miR-3182 inhibitor group exhibited much lower miR-3182 expression than cells of the inhibitor-NC group. (B) LINC00858 knockdown inhibited the proliferation of RB cells, which was reversed by co-transfection with miR-3182 inhibitor. (C and D) LINC00858 knockdown inhibited the migration and invasion of RB cells, which was reversed by miR-3182 inhibitor co-transfection. Magnification, ×100. *P<0.05. LINC00858, long intergenic non-protein coding RNA 858; si-LINC00858, small interfering RNA targeting LINC00858; si-NC, scrambled control; RB, retinoblastoma; miR, microRNA; NC, negative control.