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. 2019 Dec 11;19(2):1370–1378. doi: 10.3892/etm.2019.8317

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Treatment with 6965 decreases the levels of MDSCs. (A) Flow cytometry and fluorescent staining were used to evaluate the proportions of CD11b⁺ Gr-1⁺ MDSCs. Representative images of the bone marrow, spleen and peripheral blood from different groups are shown. Data are presented as the mean ± SD. *P<0.05 and **P<0.01. (B) The expression of Gr-1 in plaques was analyzed by immunohistochemistry and the percentage of Gr-1 positive area was calculated in the total lesioned area (magnification, ×40). Data are shown as the mean ± SD. *P<0.05 vs. the control. SD, standard deviation; CD, cluster of differentiation; MDSCs, myeloid-derived suppressor cells.