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Plasma concentration‐time profiles of single‐dose probenecid‐boosted tenofovir (TFV) (a) and on‐demand IPERGAY TFV (b) predicted by physiologically‐based pharmacokinetic model and overlaid by clinical observed data (Liu et al.21). The black open circles in a and squares in b represent the observed data. Black solid lines represent the predicted and black dash lines show the 5th and 95th confidence intervals. h, hour.
