Table 2. Comparison of pediatric Crohn's disease phenotype at diagnosis between Korea and EUROKIDS according to the Paris classification.
Paris classification | Korea (n=241) | EUROKIDS (n=582) | p-value | |
---|---|---|---|---|
Diagnosis age | <0.001 | |||
A1a | 17 (7.1) | 114 (19.6) | ||
A1b/A2 | 224 (92.9) | 468 (80.4) | ||
LGI tract location | <0.001 | |||
No involvement | 2 (0.8) | 21 (3.6) | ||
L1 | 36 (14.9) | 95 (16.3) | ||
L2 | 24 (10.0) | 159 (27.3) | ||
L3 | 179 (74.3) | 307 (52.8) | ||
UGI tract location | 0.005 | |||
No involvement | 98 (40.7) | 313 (53.8) | ||
L4a | 61 (25.2) | 129 (22.1) | ||
L4b | 55 (22.8) | 97 (16.7) | ||
L4ab | 27 (11.2) | 43 (7.4) | ||
Luminal disease behavior | 0.206 | |||
B1 | 208 (86.3) | 477 (82.0) | ||
B2 | 27 (11.2) | 77 (13.2) | ||
B3/B2B3 | 6 (2.4) | 28 (4.8) | ||
Perianal fistulizing disease | 108 (44.8) | 48 (8.2) | <0.001 |
Values are presented as number (%).
A1a: 0–9 years, A1b: 10–16 years, A2: ≥17 years, LGI: lower gastrointestinal, UGI: upper gastrointestinal, L1: distal 1/3 ileum±limited cecal disease, L2: colonic disease, L3: ileocolonic disease, L4a: upper disease proximal to the ligament of Treitz, L4b: upper disease distal to the ligament of Treitz and proximal to the distal 1/3 ileum, L4ab: upper disease involvement in both L4a and L4b, B1: nonstricturing nonpenetrating behavior, B2: stricturing behavior, B3: penetrating behavior, B2B3: both B2 and B3.