Table IV.
Sequence differences in the rrl and erm(41) genes from clinical isolates of the M. abscessus complex.
| rrla | erm(41)b | ||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain number | 2058 | 2059 | −28 | −4 | 28 | 41 | 46 | 64 | 65 | 85 | 90 | 109 | 120 | 123 | 159 | 238 | 255 | 279 | 330 | 336 | 419 | 432 | 438 | 466 | Amino acid change | ||
| CU458896c | A | A | A | C | T | C | A | C | G | G | C | G | A | A | T | A | G | G | A | T | C | G | A | G | |||
| 9016 | A | A | A | C | T | C | A | C | G | G | C | G | A | A | C | Gf | G | G | C | T | C | G | A | G | I80Vf | ||
| 8377 | A | A | A | C | T | C | A | C | G | G | C | G | A | A | T | A | G | G | A | T | C | G | A | G | |||
| 9944 | A | A | A | C | Ce | C | A | C | G | G | C | G | A | A | C | Gf | G | G | C | T | C | G | A | G | W10Re | I80Vf | |
| 71740 | A | A | A | C | T | C | A | C | G | G | C | G | A | A | C | Gf | A | T | C | C | C | G | A | G | I80Vf | ||
| 9614 | A | A | A | C | T | C | A | C | G | G | C | G | G | A | C | Gf | A | T | C | C | C | G | A | G | I80Vf | ||
| 9854 | A | A | A | C | T | C | A | C | G | G | C | G | A | A | T | A | G | G | A | T | C | G | A | G | |||
| 8548 | A | A | A | C | T | C | A | C | G | G | C | G | A | A | C | Gf | A | T | C | C | Tg | G | A | G | I80Vf | P140Lg | |
| 9419 | A | A | A | C | T | C | A | G | G | G | C | G | A | A | C | Gf | A | T | C | C | C | G | A | G | I80Vf | ||
| 74369 | A | A | G | T | T | A | G | – | – | T | T | A | A | G | – | – | – | – | – | – | – | – | C | A | |||
| 9835 | A | A | G | T | T | A | G | – | – | T | T | A | A | G | – | – | – | – | – | – | – | – | C | A | |||
| 77944 | A | A | G | T | T | A | G | – | – | T | T | A | A | G | – | – | – | – | – | – | – | – | C | A | |||
| 9626 | A | A | G | T | T | A | G | – | – | T | T | A | A | G | – | – | – | – | – | – | – | – | C | A | |||
| 9388 | A | A | G | T | T | A | G | – | – | T | T | A | A | G | – | – | – | – | – | – | – | – | C | A | |||
| 8006 | A | G | G | T | T | A | G | – | – | T | T | A | A | G | – | – | – | – | – | – | – | – | C | A | |||
| AP014547d | A | A | G | T | T | A | G | – | – | T | T | A | A | G | – | – | – | – | – | – | – | – | C | A | |||
a
Numbering system for the rrl gene from Escherichia coli;
b
Numbering system for the erm(41) gene, with the GTG start codon as 1
c
CU458896 (ATCC19977) is a reference sequence for M. abscessus subsp. Abscessus
d
AP014547 (JCM15300) is a reference sequence for M. abscessus subsp. Massiliense
e
T to C transition at position 28 (28T>C) leading to a Trp>Arg amino acid change at codon 10
f
A to G transition at position 238 (238A>G) leading to a Ile>Val amino acid change at codon 80
g
C to T transition at position 419 (419C>T) leading to a Pro>Leu amino acid change at codon 140.