Figure 4.

Loss of Als3 decreases bacterial colonization of bladder during in vivo coinfection. Mice were infected with GBS alone, C. albicans DAY185 + GBS, or C. albicans als3Δ/Δ + GBS. At 24 h, bladder, urine and kidneys were harvested and plated for GBS CFUs (A–C) and C. albicans CFU (D–F). Infections were performed three times independently and data combined (n = 16–18 mice per group). Statistical analysis between experiments was performed using the Kruskal-Wallis ANOVA with Dunn's multiple comparison **P < 0.01.