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. 2020 Jan 10;9:1466. doi: 10.3389/fonc.2019.01466

Table 1.

B7-H3 expression and clinical features in 268 gastric adenocarcinoma patient samples.

Clinical or pathological features Total No. B7-H3 expression P-value Tumor cellsa P-value Stromal cellb P-value
0 1 2 3 Lowc Highd Lowc Highd
All cases 268 38 46 151 33 218 50 100 168
Age 0.723 0.609 0.180
<70 164 24 23 98 19 135 29 56 108
≥70 104 14 23 53 14 83 21 44 60
Sex 0.641 0.285 0.678
Male 58 6 13 36 3 50 8 23 35
Female 210 32 33 115 30 168 42 77 133
Tumor volume (cm3) 0.087 0.023 0.478
<5 186 35 29 96 26 158 28 72 114
≥5 82 3 17 55 7 60 22 28 54
Tumor differentiation 0.066 0.733 0.077
Well 6 2 0 4 0 5 1 3 3
Moderate 121 14 16 69 22 97 24 36 85
Poor 141 22 30 78 11 116 25 61 80
Tumor stage 0.000 0.002 0.009
0 11 5 3 3 0 11 0 8 3
I 32 6 7 16 3 30 2 14 18
II 66 12 13 35 6 55 11 28 38
III 123 13 16 75 19 97 26 38 85
IV 36 2 7 22 5 25 11 12 24
Tumor depth 0.001 0.001 0.009
T1 36 9 9 16 2 34 2 19 17
T2 34 7 9 16 2 33 1 16 18
T3 169 19 26 98 26 130 39 57 112
T4 29 3 2 21 3 21 8 8 21
LN involvement 0.020 0.006 0.170
N0 85 18 16 43 8 74 11 38 47
N1 62 10 9 35 8 55 7 22 40
N2 56 7 6 32 11 42 14 17 39
N3 65 3 15 41 6 47 18 23 42
Metastasis 0.269 0.091 0.634
M0 238 37 39 133 29 197 41 90 148
M1 30 1 7 18 4 21 9 10 20
Death 0.003 0.020 0.089
78 18 13 40 7 69 9 34 44
+ 120 10 20 70 20 90 30 38 82
a

B7-H3 expression on tumor cells.

b

B7-H3 expression on stromal cells.

c

B7-H3 low expression.

d

B7-H3 high expression.