Table 1.
Clinical or pathological features | Total No. | B7-H3 expression | P-value | Tumor cellsa | P-value | Stromal cellb | P-value | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | Lowc | Highd | Lowc | Highd | |||||
All cases | 268 | 38 | 46 | 151 | 33 | 218 | 50 | 100 | 168 | |||
Age | 0.723 | 0.609 | 0.180 | |||||||||
<70 | 164 | 24 | 23 | 98 | 19 | 135 | 29 | 56 | 108 | |||
≥70 | 104 | 14 | 23 | 53 | 14 | 83 | 21 | 44 | 60 | |||
Sex | 0.641 | 0.285 | 0.678 | |||||||||
Male | 58 | 6 | 13 | 36 | 3 | 50 | 8 | 23 | 35 | |||
Female | 210 | 32 | 33 | 115 | 30 | 168 | 42 | 77 | 133 | |||
Tumor volume (cm3) | 0.087 | 0.023 | 0.478 | |||||||||
<5 | 186 | 35 | 29 | 96 | 26 | 158 | 28 | 72 | 114 | |||
≥5 | 82 | 3 | 17 | 55 | 7 | 60 | 22 | 28 | 54 | |||
Tumor differentiation | 0.066 | 0.733 | 0.077 | |||||||||
Well | 6 | 2 | 0 | 4 | 0 | 5 | 1 | 3 | 3 | |||
Moderate | 121 | 14 | 16 | 69 | 22 | 97 | 24 | 36 | 85 | |||
Poor | 141 | 22 | 30 | 78 | 11 | 116 | 25 | 61 | 80 | |||
Tumor stage | 0.000 | 0.002 | 0.009 | |||||||||
0 | 11 | 5 | 3 | 3 | 0 | 11 | 0 | 8 | 3 | |||
I | 32 | 6 | 7 | 16 | 3 | 30 | 2 | 14 | 18 | |||
II | 66 | 12 | 13 | 35 | 6 | 55 | 11 | 28 | 38 | |||
III | 123 | 13 | 16 | 75 | 19 | 97 | 26 | 38 | 85 | |||
IV | 36 | 2 | 7 | 22 | 5 | 25 | 11 | 12 | 24 | |||
Tumor depth | 0.001 | 0.001 | 0.009 | |||||||||
T1 | 36 | 9 | 9 | 16 | 2 | 34 | 2 | 19 | 17 | |||
T2 | 34 | 7 | 9 | 16 | 2 | 33 | 1 | 16 | 18 | |||
T3 | 169 | 19 | 26 | 98 | 26 | 130 | 39 | 57 | 112 | |||
T4 | 29 | 3 | 2 | 21 | 3 | 21 | 8 | 8 | 21 | |||
LN involvement | 0.020 | 0.006 | 0.170 | |||||||||
N0 | 85 | 18 | 16 | 43 | 8 | 74 | 11 | 38 | 47 | |||
N1 | 62 | 10 | 9 | 35 | 8 | 55 | 7 | 22 | 40 | |||
N2 | 56 | 7 | 6 | 32 | 11 | 42 | 14 | 17 | 39 | |||
N3 | 65 | 3 | 15 | 41 | 6 | 47 | 18 | 23 | 42 | |||
Metastasis | 0.269 | 0.091 | 0.634 | |||||||||
M0 | 238 | 37 | 39 | 133 | 29 | 197 | 41 | 90 | 148 | |||
M1 | 30 | 1 | 7 | 18 | 4 | 21 | 9 | 10 | 20 | |||
Death | 0.003 | 0.020 | 0.089 | |||||||||
– | 78 | 18 | 13 | 40 | 7 | 69 | 9 | 34 | 44 | |||
+ | 120 | 10 | 20 | 70 | 20 | 90 | 30 | 38 | 82 |
B7-H3 expression on tumor cells.
B7-H3 expression on stromal cells.
B7-H3 low expression.
B7-H3 high expression.