Figure 3.

SMLM data point coordinates of γ-H2AX and 53BP1, MRE11 and p-ATM in alpha-trajectories. Representation of SMLM signal point positions in Cartesian coordinates over the whole nucleus for (A) γ-H2AX, (B) 53BP1, (C) MRE11, and (D) p-ATM. Following the masking procedure applied (c.f. Figure 2A), SMLM signal point coordinates are differentially colored for those present in γ-H2AX-marked damage track mask (green) and those detected throughout the nucleus (blue). The small grey-boxed sub-regions are blown up for better display to the right.