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. 2019 Dec 6;11(12):1957. doi: 10.3390/cancers11121957
EOC Epithelial Ovarian Cancer
HGSOC High-grade serous ovarian carcinomas
PTEN Phosphatase and tensin homolog
CTNNB1 Catenin beta 1
TP53 Tumor protein P53
KRAS Kirsten rat sarcoma viral oncogene homolog
BRAF Serine/threonine protein kinase B-Raf
CDKN2A Cyclin-dependent kinase inhibitor 2A
ARID1A AT-rich interaction domain 1A
PIK3CA Phosphatidylinositol-4,5-3-kinase catalytic subunit alpha
BRCA1, BRCA2 Breast cancer type susceptibility proteins 1/2
CNV Gene copy number variation
FTSEC Fallopian tube secretory epithelial cells
STIC Serous tubal intraepithelial tubal carcinoma
NMMII Non-muscle myosin II
Src Src proto-oncogene
ROCK Rho-associated kinase
Erbb2 Erb-B2 receptor tyrosine kinase 2
ECM Extracellular matrix
CRC Colorectal cancer
ParD6 Partitioning defective 6 homolog alpha
TGFβ Tumor growth factor β
TGFβR2 Tumor growth factor β receptor 2
SMAD2 Mothers against decapentaplegic homolog 2
MT1-MMP Membrane type 1 matrix metalloproteinase
LPA Lysophosphatidic acid
Edg 2,4,7 Endothelial differentiation gene family member 2,4,7
G-proteins Heterotrimeric guanine nucleotide binding regulatory proteins
PI3K Phosphoinositide 3 kinase
m-p53 Mutant p53
APC6 Lysophosphatidic acid phosphatase type 6
FAK Focal adhesion kinase
EGF Epidermal growth factor
VEGF Vascular endothelial growth factor
IL-6 Interleukin-6
IL-6R Interleukin-6 receptor
TNFα Tumor necrosis factor alpha
JAKs Janus kinases
PDK1 Phosphoinositide-dependent kinase-1
Akt also known as protein kinase B (PKB)
Bcl-2 Bcl-2 (B-cell lymphoma 2)
Bcl-XL B-cell lymphoma-extra large
Bax Bcl-2-associated X, apoptosis regulator
Bad Bcl-2 associated agonist of cell death
JNK c-Jun N-terminal kinase
STAT3 Signal transduction activation of transcription 3
MAPK Mitogen-activated protein kinase
CCL2 C–C motif chemokine ligand 2
CXCL12 SDF1 C–X–C motif chemokine ligand 12, also known as stromal cell-derived factor 1
TNFR1 TNF receptor 1
TAMs Tumor-associated macrophages
MLC Myosin light chain
EMT Epithelial-to-mesenchymal transition
CAF Cancer-associated fibroblasts
FABP4 Fatty acid-binding protein 4
SIK2 Salt-inducible kinase 2
NETs Neutrophil extracellular traps
CDC42 Cell division control protein 42