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. 2019 Dec 12;11(12):1998. doi: 10.3390/cancers11121998

Figure 1.

Figure 1

DDB1 expression is increased in PDAC tissues. (A) DDB1 transcription was increased significantly in pancreatic cancer tissues compared to that in normal tissues in the GEPIA dataset. (B) DDB1 transcription was varied in different stages in the GEPIA dataset. (C) High mRNA expression of DDB1 was associated with shorter OS (p = 0.012) but not DFS (p = 0.22). (D) Representative images of IHC staining for DDB1 in TMAs (inset scale bar, 40 µm). (E) DDB1 mRNA expression levels in PDAC and adjacent normal tissues (n = 45, p = 0.004). (F) The OS of patients with PDAC was assessed using a Kaplan-Meier analysis based on DDB1 expression (n = 147, p = 0.002). (G) DDB1 expression in PDAC and adjacent normal tissues, as determined by the IHC score (n = 147, p < 0.001).