Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
DDB1 knockdown increases the sensitivity of PDAC cells to GEM. (A) MiaPaCa-2 and PANC-1 cells were treated with GEM for 0–4 days. (B) A colony formation assay was conducted to confirm the effect of DDB1 abrogation and the effect of GEM on PDAC cell lines; quantitation of the data is shown in (C). (D) Apoptosis rates of the DDB1-silenced cell lines with or without GEM treatment; quantitation of the data is shown in (E). * p < 0.05, ** p < 0.01, *** p < 0.001.
