Table 2.
Univariate and multivariate Cox regression of overall survival for PDAC patients.
| Features | N | Univariable Analysis | Multivariable Analysis | ||
|---|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | ||
| All | |||||
| Age (years) | |||||
| >60 | 77 | 1.134 (0.805–1.596) | 0.472 | ||
| ≤60 | 70 | ||||
| Sex | |||||
| Female | 64 | 1.184 (0.836–1.677) | 0.341 | ||
| Male | 83 | ||||
| AJCC stage | |||||
| IIB-III | 69 | 1.883 (1.334–2.660) | <0.001 | 1.846 (1.307–2.609) | 0.001 |
| I-IIA | 78 | ||||
| Grade | |||||
| Low | 59 | 1.223 (0.862–1.735) | 0.259 | ||
| High/moderate | 88 | ||||
| Tumor size (cm) | |||||
| ≥4 | 48 | 1.496 (1.038–2.157) | 0.031 | 1.522 (1.054–2.197) | 0.025 |
| <4 | 99 | ||||
| Vascular emboli | |||||
| Yes | 26 | 1.248 (0.800–1.945) | 0.329 | ||
| No | 121 | ||||
| DDB1 expression | |||||
| High | 113 | 1.990 (1.288–3.076) | 0.002 | 1.909 (1.235–2.950) | 0.004 |
| Low | 34 | ||||
| CA19-9≥37 U/mL | |||||
| Yes | 112 | 0.933 (0.626–1.390) | 0.732 | ||
| No | 35 | ||||
HR, hazard ratios; CI, confidential intervals.