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Schematic illustration of the nuclear receptor hormone family. Structural differences within the nuclear receptor hormone family occur at the NTD, DBD, and LBD. The functional differences are defined based on co-activator recruitment, dimeric receptor interactions, and ligand binding. Abbreviations: NTD, N-terminal domain; DBD, DNA-binding domain; H, Hinge region; LBD, Ligand-binding domain; C, Variable C-terminus; HRE, Hormone Response Elements.
