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. 2019 Dec 4;11(12):1931. doi: 10.3390/cancers11121931

Figure 1.

Figure 1

Capsular invasion in advanced ACC. (A) Representative Hematoxylin/Eosin staining of an advanced stage 3-ACC showing disruption of the capsule with pushing a well-circumscribed tumor border (*) into the surrounding adipose tissue. (B) Representative Hematoxylin/Eosin staining of an advanced stage 4-ACC displaying cancer extension beyond the capsule with irregular clusters and cords of tumor cells infiltrating the fat. Arrowheads indicate the remaining adrenal capsule. Scale bars = 300 μm (A) and 400 μm (B).