CAFs |
Cancer-associated Fibroblasts |
CRC |
Colorectal Cancer |
CSFR1 |
Colony Stimulating Factor 1 Receptor |
CTLA-4 |
Cytotoxic T-lymphocyte-associated Protein 4 |
CXCL |
Chemokine C-X-C Motif Ligand |
CXCR |
C-X-C Chemokine Receptor |
EGFR |
Epidermal Growth Factor Receptor |
ERBB |
Erythroblastic Leukemia Viral Oncogene Homologue Receptors |
FAP |
Fibroblast Activation Protein |
GDP |
Guanosine diphosphate |
GLI1 |
GLI family zinc finger 1 |
GM-CSF |
Granulocyye Macrophage Colony-stimulating Factor |
GTP |
Guanosine triphosphate |
Hh |
Hedgehog |
HIF-1α |
Hypoxia Inducible Factor 1 Subunit Alpha |
HRAS |
Harvey Rat Sarcoma Viral Oncogene Homolog |
IGFR |
Insulin-like Growth factor |
IL |
Interleukin |
IRF2 |
Interferon Regulatory factor 2 |
KRAS |
Kirsten Rat Sarcoma Viral Oncogene Homolog |
MDSCs |
Myeloid-derived Suppressor Cells |
MET |
Hepatocyte Growth Factor Receptor |
MHC I |
Major Histocompatibility Class I |
MMR |
Mismatch Repair |
NRAS |
Neuroblastoma Rat Sarcoma Viral Oncogene Homolog |
NSCLC |
Nonsmall Cell Lung Cancer |
PD-1 |
Programmed Cell Death Protein 1 |
PDAC |
Pancreatic Ductal Adenocarcinoma |
PD-L1 |
Programmed Cell Death Protein Ligand 1 |
RAS |
Rat Sarcoma Viral Oncogene Homolog |
RTK |
Receptor Tirosine Kinase |
SHH |
Sonic Hedgehog |
STING |
Stimulator of Interferon Genes |
TGFβ1 |
Transforming Growth Factor Beta 1 |
TME |
Tumor Microenvironment |
Tregs |
T regulatory cells |