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LSD1 regulates CSC properties. Key processes of CSCs are maintained and/or promoted by the function of LSD1 (shown in green circles) in the depicted types of cancer. Depletion of the enzyme affects stemness-related characteristics (shown in red circles). LSCs: Leukemic stem cells, GSCs: Glioblastoma stem cells, HCC-CSCs: Hepatocellular carcinoma CSCs, and b-CSCs: Breast CSCs (downward arrow: Decrease, upward arrow: Increase).
