Table 1.
Summary of patient tissue data and corresponding PET and MRS results from each sample. M = mutant, WT = wild type, R = retained, CD = codeleted, U = unknown, ChoKα = negative, DNET = diffuse neuroepithelial tumour. Patient 6 (P006) did not have a PET scan, and the location of the surgical resection was not recorded, excluding them from tissue vs. imaging analyses. P007 did not undergo surgical resection at our institution and hence no tissue data were available. P013 (DNET) was excluded from the analyses. Grey cells: data unavailable.
| Subject | Tumour Type, WHO Grade | Molecular | Sample 1 | Sample 2 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| IDH1 | 1p/19q | ATRX | SBR (PET) | Cho/Cr (MRS) | ChoKα | SBR (PET) | Cho/Cr (MRS) | ChoKα | ||
| P001 | Astrocytoma, II | M | R | M | 1.6 | 1.05 | - | 1 | 1.86 | - |
| P002 | Oligodendroglioma, III | M | U | WT | 3.4 | 1.8 | - | 2.2 | 0.42 | - |
| P003 | Oligodendroglioma, III | M | CD | WT | 4.4 | 1.65 | - | 3.6 | 1.68 | weak |
| P004 | Astrocytoma, III | WT | R | M | 0.8 | 0.9 | - | 0.8 | 1.59 | - |
| P005 | Oligodendroglioma, II | M | R | M | 1 | 0.96 | - | 1.1 | 1.23 | weak |
| P006 | Oligodendroglioma, II | M | U | WT | unrecorded location | weak | unrecorded location | weak | ||
| P007 | Astrocytoma, II | surgery at external institution | ||||||||
| P008 | GBM | M | R | M | 5.6 | 1.02 | weak | no second sample | ||
| P009 | GBM | WT | R | M | 9.3 | N/A | weak | 7.3 | 1.77 | weak |
| P010 | GBM | WT | R | U | 43 | 2.88 | strong | 20 | 2.7 | - |
| P011 | Astrocytoma, III | M | R | M | 3.1 | 1.89 | - | 3.9 | 2.91 | weak |
| P012 | Astrocytoma, II | M | R | M | 1.3 | 1.53 | - | 1.2 | 0.75 | weak |
| P013 | DNET, I | excluded from analyses | ||||||||
| P014 | Astrocytoma, II | M | R | M | 2.7 | 0.84 | - | no second sample | ||