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. 2019 Dec 4;11(12):1936. doi: 10.3390/cancers11121936

Figure 5.

Figure 5

Knosp classification of CS extension of PAs. Initially described in 1993, Knosp grading of PAs extending in the cavernous sinus was modified in 2015 by the same group. Novel data, acquired in the endoscopic era, have shown that grade 3A PAs are less frequently invasive than grade 3B. This difference might be related to the different anatomy of the MWCS, as grade 3A tumors might displace it or extend in the cavernous sinus through defects (see also Graphical Abstract and text for further details).