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. 2019 Nov 27;11(12):1891. doi: 10.3390/cancers11121891

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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IHC examination of CDX2 in patients with stage II/III CRC: (a) Schematic representation of the workflow of immunohistochemistry of CDX2. (b) Expression of CDX2 in CRC specimens. Normal intestinal epithelial cells were used as an internal positive control. A Score 0 and B Score 0.5; were determined to be CDX2-negative. C Score 2 and D Score 3; were determined to be CDX2-positive. The scale bar represents 100 µm. (c,d) Kaplan–Meier curves for OS and RFS of the 174 patients with stage II/III CRC. CDX2: caudal-type homeobox transcription factor 2; CRC: colorectal cancer; OS: overall survival; RFS: relapse-free survival.