Table 2.

Histopathological evaluation of tumors with B-raf V600E mutation.

Group	Cell Size Variation (>7 µm)	Neo-Vascularization	Discohesive Pattern	Mutli-Nucleation	Heterogeneity Score (0–4)
B-raf V600E high	5/9 (56%)	7/9 (77%)	6/9 (66%)	3/9 (33%)	3
B-raf V600E low	3/7 (43%)	1/7 (14%)	2/7 (29%)	5/7 (71%)	1

Tumors expressing high or low levels of B-raf V600E (rows) displayed heterogeneous properties with respect to tumor cohesion, vasculature, and cellular morphology (columns). The individual factors can be summed to give the heterogeneity score (final column).