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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Single and multiple dose area under the concentration time curve (AUC0-24h) of BAY 1125976 in the QD (A) and the BID (B) schedule, including patients at the 60 mg BID expansion cohort, showing dose linearity for both schedules. C, cycle; D, day; Exp, expansion cohort.