Table 3.

Feature requirements derived from the use cases developed.

Use Cases/Requirements	Functionality	Description
Researcher and patient data access	Reports	Reports, based on the data in the system for the centre, can be generated in real-time. Graphs and tables can be visualised online
Patient permissions	Consent form	Ensure the patient has choice and control over their data
Researcher finds patient matching certain inclusion parameters	Search	Access to aggregated, anonymised, or pseudo-anonymised data
Longitudinal data	Follow up mechanism	A non-intrusive mechanism for follow-ups
		Give choice for being contacted, select frequency and reason
Patient registration	Registration	Pseudo-anonymisation
Researcher accessing user data	Clinical trial recruitment	Pseudo-anonymised user data list and communication
Addressing selection bias	Dynamic landing pages based on patient source	Different calls to action in recruitment channels (especially online) can be reinforced by custom landing pages
Longitudinal data	AppleHealth integration (on mobile devices)	Connector and UI