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. 2019 Dec 1;11(12):1912. doi: 10.3390/cancers11121912

Table 1.

Classification of cytological results and correlation with histological results. RON: risk of neoplasm; ROM: risk of malignancy.

Cytopathology Histopathology RON ROM
Milan System Category Number of Cases (%) Number of Cases per Category (%) Not Performed Non-Neoplastic Benign Neoplasm Malignant RON (%) RON per Category (%) ROM (%) ROM per Category (%)
Non-Diagnostic (ND) Pauci-cellular 55 (16.8) 84
(25.6)
24 2 20 9 29/31 (93.5) 38/47
(80.9)
9/31 (29) 16/47 (34)
Cystic content 25 (7.6) 13 3 6 3 9/12 (75) 3/12 (25)
Lymphocytes 4 (1.2) - - - 4 4/4 (100) 4/4 (100)
Non-Neoplastic (NN) Normal lymph node 7 (2.1) 27 (8.2) 5 2 - - 0/9 (0) 1/9 (11.1) 0/9 (0) 0/9 (0)
Reactive lymph node/Inflammation 12 (3.7) 10 2 - - 0/9 (0) 0/9 (0)
Lithiasis/sialadenitis 1 (0.3) 1 - - - 0/9 (0) 0/9 (0)
Cyst 7 (2.1) 2 4 1 - 1/9 (11.1) 0/9 (0)
Atypia of Undetermined Significance (AUS) 4 (1.2) 4 (1.2) 2 - 2 - 2/2 (100) 2/2 (100) 0/2 (0) 0/2 (0)
Benign Neoplasm (BN) Pleomorphic adenoma 89 (27.1) 145
(44.2)
18 - 67 4 71/71 (100) 105/105 (100) 4/71 (5.63) 4/105 (3.09)
Warthin’s tumour 55 (16.8) 21 - 34 - 34/34 (100) 0/34 (0)
Schwanomma 1 (0.3) 1 - - - - -
Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP) Oncocytic 7 (2.1) 15 (4.6) 3 2 1 1 2/4 (50) 7/11 (63.6) 1/4 (25) 5/11 (45.5)
Unspecified 8 (2.4) 1 2 1 4 5/7 (71.4) 4/7 (57.1)
Suspicious for malignancy (SM) Epithelial 6 (1.8) 16 (4.9) 1 2 3 5/6 (83.3) 13/16 (81.3) 3/6 (50) 11/16
(68.8)
Lymphoma 10 (3.1) - 2 - 8 8/10 (80) 8/10 (80)
Malignant (M) Low-grade 1 (0.3) 37
(11.3)
- - - 1 1/1 (100) 26/26 (100) 1/1 (100) 26/26
(100)
High-grade 23 (7) 4 - - 19 19/19 (100) 19/19 (100)
Metastasis 13 (4) 7 - - 6 6/6 (100) 6/6 (100)
Total 328 (100) 328 (100) 112 (34.2) 18 (5.5) 136 (41.5) 62 (18.9) -