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. 2019 Dec 1;11(12):1912. doi: 10.3390/cancers11121912

Table 4.

Cases with Immunocytochemistry and FISH. BN: Benign-Neoplasm; SUMP: Salivary Gland Neoplasm of Uncertain Malignant Potential; M: Malignant; LG: Low-grade HG: High-grade; PA: pleomorphic adenoma; AdCC: adenoid cystic carcinoma; SC: secretory carcinoma; ADK, NOS: adenocarcinoma not otherwise specified; neg: negative; pos: positive.

Patient Milan System Category Cytological Diagnosis Histological Diagnosis Immunocytochemistry FISH
Antibody Used Results Contribution Probe Used Results Contribution
116 BN PA PA Ki67 1% pos Eliminated HG-M PLAG1 neg No help
117 BN PA PA Ki67 2% pos Eliminated HG-M PLAG1 neg No help
118 BN PA not performed p63 pos provided the diagnosis PLAG1 pos Provided the diagnosis
119 BN PA not performed Ki67 2% pos Eliminated HG-M PLAG1 pos Provided the diagnosis
120 BN PA not performed Ki67 1% pos Eliminated HG-M PLAG1 pos Provided the diagnosis
121 BN PA PA Ki67 3% pos Eliminated HG-M PLAG1 pos Provided the diagnosis
264 SUMP SUMP with Oncocytic features Cellular PA with oncocytyc cells Ki67 3% pos Eliminated HG-M PLAG1 neg No help
293 M (HG) AdCC AdCC Ki67 10% pos In favor of HG-M MYB pos Provided the diagnosis
PLAG1 neg
294 M (HG) AdCC AdCC p63 pos did not contribute to diagnosis MYB pos Provided the diagnosis
295 M (LG) SC SC MAM 30% pos provided the diagnosis ETV6 pos Provided the diagnosis
299 M (HG) ADK, NOS metastasis of lung adeno-carcinoma Ki67 20% pos In favor of HG-M ETV6 neg No help