Table 2.
Early lung function changes evaluated on the day after bronchial thermoplasty
| Day before BT (baseline) | Day after BT | Change from baseline | |
|---|---|---|---|
| First procedure at right lower lobe (13 sessions) | |||
| FVC (l) | 3.23 ± 1.13 | 2.83 ± 1.13 | − 0.39 ± 0.39 |
| %FVC (%) | 95.0 ± 12.5 | 82.5 ± 15.7 | − 12.5 ± 11.4 |
| FEV1 (l) | 2.14 ± 1.03 | 1.85 ± 0.87 | − 0.29 ± 0.26 |
| %FEV1 (%) | 74.5 ± 22.7 | 64.6 ± 20.5 | − 10.0 ± 7.6 |
| %PEF (%) | 76.6 ± 20.9 | 67.7 ± 20.1 | − 9.0 ± 8.0 |
| Second procedure at left lower lobe (13 sessions) | |||
| FVC (l) | 3.29 ± 1.11 | 2.94 ± 1.01 | − 0.36 ± 0.27 |
| %FVC (%) | 97.5 ± 12.0 | 86.6 ± 11.5 | − 10.8 ± 7.7 |
| FEV1 (l) | 2.21 ± 0.90 | 1.97 ± 0.77 | − 0.25 ± 0.33 |
| %FEV1 (%) | 78.2 ± 19.5 | 69.2 ± 17.0 | − 9.0 ± 9.9 |
| %PEF (%) | 78.1 ± 19.8 | 72.2 ± 19.5 | − 6.0 ± 11.1 |
| Third procedure at bilateral upper lobes (13 sessions) | |||
| FVC (l) | 3.41 ± 1.29 | 2.82 ± 1.05 | − 0.59 ± 0.40 |
| %FVC (%) | 100.1 ± 11.8 | 86.6 ± 11.5 | − 17.0 ± 9.1 |
| FEV1 (l) | 2.45 ± 1.00 | 1.92 ± 0.83 | − 0.53 ± 0.32 |
| %FEV1 (%) | 85.2 ± 17.1 | 67.1 ± 17.0 | − 18.1 ± 7.6 |
| %PEF (%) | 82.2 ± 18.0 | 68.4 ± 17.8 | − 13.9 ± 7.7 |
| All procedures (39 sessions) | |||
| FVC (l) | 3.31 ± 1.16 | 2.86 ± 1.07 | − 0.44 ± 0.37 |
| %FVC (%) | 97.4 ± 12.3 | 84.1 ± 13.7 | − 13.3 ± 9.9 |
| FEV1 (l) | 2.26 ± 0.98 | 1.91 ± 0.83 | − 0.35 ± 0.33 |
| %FEV1 (%) | 79.2 ± 20.4 | 66.9 ± 18.4 | − 12.2 ± 9.4 |
| %PEF (%) | 78.9 ± 20.0 | 69.4 ± 19.3 | − 9.5 ± 9.6 |
Values are presented as mean ± SD unless otherwise indicated
BT bronchial thermoplasty, FVC forced vital capacity, %FVC percent forced vital capacity, FEV1 forced expiratory volume in 1 s, %FEV1 percent forced expiratory volume in 1 s, %PEF percent peak expiratory flow