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. 2020 Jan 16;20:26. doi: 10.1186/s12870-019-2223-y

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Proposed working model of FER function in Arabidopsis flowering. FER fluctuated at a diurnal rhythm along with FER, and the clock oscillator CCA1 appears to bind the FER chromatin and promote its expression. In turn, FER will down-regulate CCA1 expression and regulate flowering through the GI-CO pathway. Thus, FER-CCA1 appears to form an interlocking feedback loop during flowering time control. In addition, FER is a negative regulator of FLC and MAF by regulating their splicing and transcript accumulation. Thus, FER functions in flowering transition by splicing pre-mRNA of genes and regulating expression of flowering-related genes. Arrows denote activation, and bars indicate repression. Details are provided in the text