Figure 1.

Hypothetical stages to fabricate functional tissues with 3DBP guided by MI. (1) Generation of a blueprint for regeneration: We may acquire data from publicly available database and experimental data from imaging (e.g., microCT or MRI) and spectroscopy (e.g., FT-IR, adapted with permission from Berisha et al., 2019). Then, acquired data will be processed to extract specific features that we can translate into a blueprint. (2) MI-guided 3DBP: To fabricate an organ-size, functional tissue from a complex blueprint, we need to optimize printing parameters leveraging MI. This approach benefits from the capacity of identifying complex data patterns to predict certain parameter space, which may not be possible to obtain without MI and which may accelerate the production of functional tissues.