Endocrine treatments (corticosteroids) are a mainstay of anti-inflammatory management for moderate and severe asthma.

Their use has improved asthma outcomes.

Androgens also reduce airway inflammation and promote airway smooth muscle relaxation, but are rarely used clinically.

Our results suggest that the over-the-counter steroid DHEA may also improve lung function in asthma outcomes among women with DHEAS < 200 ug/dL.