Table 2.
Correlation and prognostic value of deiodinase/ sodium iodide symporter expression with human epidermal growth factor receptor-2 status of gastric cancer patients
| DIOs/NIS | HER2 status | Cases | HR (95% CI) | P |
|---|---|---|---|---|
| NIS | Negative | 532 | 1.65 (1.32-2.07) | 9.5e-06 |
| Positive | 344 | 2.02 (1.49-2.75) | 3.9e-06 | |
| DIO1 | Negative | 532 | 1.47 (1.17-1.85) | 0.00097 |
| Positive | 344 | 1.42 (1.08-1.85) | 0.01 | |
| DIO2 | Negative | 532 | 1.5 (1.18-1.91) | 0.001 |
| Positive | 344 | 1.42 (1.09-1.85) | 0.0094 | |
| DIO3 | Negative | 532 | 1.69 (1.35-2.11) | 4.5e-06 |
| Positive | 344 | 1.27 (0.99-1.72) | 0.11 |
NIS: Sodium iodide symporter; CI: Confidence interval; HR: Hazard ratio; DIOs: Deiodinases; HER2: Human epidermal growth factor receptor-2