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. 2020 Jan 7;11(1):15–21. doi: 10.18632/oncotarget.27408

Table 2. HDT regulation of AR expression and response to antiandrogen post-HDT.

Patient AR Alteration ctDNA%/PCN
Pre-HDT
HDT
Responder
ctDNA%/PCN
Post-HDT
Abi or Enza
Post-HDT
PSA50
Responder
1 Amplification 3.9 N ND Enza Y
2 AR (W742C) 1.30% PSA50 ND Abi N/A
3 Amplification 1.6 PSA30 ND Abi N
4 Amplification 1.5 PSA50 ND Abi N/A
5 AR (L702H) 34.90% N 6.80% Enza N
AR (V716M) 1.20% ND
6 Amplification 36.2 N 8.7 Enza N/A
7 Amplification 1.4 N ND Enza Y
AR (W742L) ND 1.20%
8 AR (T878A) 0.80% PSA30 ND Enza N/A
9 AR (W742C) 0.50% PSA30 ND Enza N/A
AR (M896V) 5.30% ND