Table 2.
List of top 10 up-regulated proteins based on fold change in EVs from reactive astrocytes compare to control astrocyte.
| Uniprotein_ID | Symbol | Entrez gene name | Location | Type(s) | p-value | Fold change |
|---|---|---|---|---|---|---|
| P29401 | TKT | Transketolase | Cytoplasm | Enzyme | 3.05E−03 | 2.25E+06 |
| Q03135 | CAV1 | Caveolin 1 | Plasma Membrane | Transmembrane receptor | 4.67E−02 | 1.83E+06 |
| P05388 | RPLP0 | Ribosomal protein lateral stalk subunit P0 | Cytoplasm | Other | 3.27E−02 | 7.95E+05 |
| P60174 | TPI1 | Triosephosphate isomerase 1 | Cytoplasm | Enzyme | 5.12E−05 | 7.95E+05 |
| O00299 | CLIC1 | Chloride intracellular channel 1 | Nucleus | Ion channel | 4.96E−03 | 6.02E+05 |
| Q9H4M9 | EHD1 | EH domain containing 1 | Cytoplasm | Other | 4.99E−02 | 4.89E+05 |
| Q01518 | CAP1 | Cyclase associated actin cytoskeleton regulatory protein 1 | Plasma Membrane | Other | 4.69E−02 | 2.28E+05 |
| P18669 | PGAM1 | Phosphoglycerate mutase 1 | Cytoplasm | Phosphatase | 3.27E−02 | 3.63E+01 |
| Q16658 | FSCN1 | Fascin actin-bundling protein 1 | Cytoplasm | Other | 2.16E−02 | 2.13E+01 |
| P30447 | HLA-A | Major histocompatibility complex, class I, A | Plasma Membrane | Other | 3.50E−02 | 1.89E+01 |