Table 4.
Compounds TKR19–TKR21 and their anti-tumour activity.
 | ||||
|---|---|---|---|---|
| Compound | R9 | X | R10 | IC50 (μM) |
| TKR19 | –CH3 | O | –Cl | >100 |
| TKR20 | –CF3 | O | –H | 22.75 |
| TKR21 | –CF3 | S | –H | 18.57 |
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