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. 2020 Jan 14;8:e8370. doi: 10.7717/peerj.8370

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©2020 Shi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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Comparison of the average V-J gene utilization of the sequenced IGH sequences between the SSc group and the Control group. The J gene segments are arranged on the y-axis, and the V gene segments are arranged on the x-axis. The different colors (red to blue rectangular bands) indicate the different levels of significance. Rectangular bands is the value converted from −log10 (p value), “+” indicates significant difference (SSc group is higher than the Control group), and “−” indicates significant difference (Control group is higher than SSc). Differences were statistically analyzed for significance by the Wilcoxon rank sum test (p < 0.05).