Table 3. IGHV-J pairing usage differences between SSc and Control groups.

IGHV-J pairing	SSc (mean ± s.d)%	Control (mean ± s.d)%	P
IGHV1-18-J3	0.35 ± 0.08	0.19 ± 0.09	0.016
GHV1-8-J2	0.16 ± 0.12	0.02 ± 0.03	0.028
GHV1-8-J4	1.07 ± 0.42	0.35 ± 0.39	0.016
IGHV3-53-J4	1.05 ± 0.24	0.59 ± 0.13	0.016
IGHV3-9-J3	0.26 ± 0.09	0.04 ± 0.05	0.016
IGHV3-9-J4	1.98 ± 0.92	0.62 ± 0.84	0.042
IGHV3-9-J5	0.41 ± 0.18	0.10 ± 0.14	0.028
IGHV4-61-J4	1.65 ± 0.33	1.18 ± 0.19	0.042
IGHV2-5-J6	0.22 ± 0.12	0.47 ± 0.06	0.004
IGHV2-70-J5	0.11 ± 0.09	0.27 ± 0.11	0.028
IGHV3-20-J6	0.07 ± 0.06	0.36 ± 0.31	0.016
IGHV3-23-J6	0.95 ± 0.46	1.78 ± 0.33	0.016
IGHV3-7-J5	1.08 ± 0.17	1.61 ± 0.43	0.042
IGHV4-4-J6	0.95 ± 0.46	2.13 ± 0.58	0.016