Method	Description
A.Emulsion-Solvent Evaporation Method:	It entails 2 steps. This method is modified into emulsification with high pressure and another method known as solvent evaporation [61].
B. Twofold Emulsion and Dissipation Technique:	This method based on encapsulation of water soluble drugs through mixing of organic polymer solutions with hydrophilic drug solution this step is followed by stirring powerfully to form water/oil emulsions [62].
C. Salting Out Technique:	Basically depend on isolation of a solvent of water miscible property from watery solution through a salting out impact [63].
D. Emulsions Diffusion Method:	It relies upon dissolving the polymer in part in a water-miscible dissolvable and completely immersed with water. In the long run shaped an emulsion in a watery arrangement that contains a stabilizer, prompting dissolvable dissemination to outside stage and development of nano spheres or Nano capsules. Detriments are exorbitant volumes of water to be disposed of, bringing down exemplification execution [64].
E. Solvent Displacement/Precipitation method:	Includes precipitation of a preformed polymer from a characteristic arrangement and dispersion of normal dissolvable in a fluid medium inside the nearness or non-attendance of surfactant. Medication is disintegrated in a semi-polar water dissolvable including CH3)2CO or ethanol. This strategy is proper for ineffectively dissolvable medications [65].