Figure 5.

Expression levels of melanogenesis-related proteins in B16BL6 murine melanoma cells.

Western blot analysis performed on B16BL6 murine melanoma cells treated with LEVs at 1, 5 and 10 μg/mL for 24 h. (a) Effect of LEVs on MITF protein levels. (b) Effect of LEVs on TYR protein levels. (c) Effect of LEVs on TRP-1 protein levels. (d) Effect of LEVs on TRP-2 protein levels Western blot analysis were applied. *, ** and *** indicate difference for p < 0.05, p < 0.01 and p < 0.001 in comparison to the cells treated with cell culture media as negative control. The cells treated with arbutin were used as a positive control (n = 3).