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. 2020 Jan 6;42(1):98–106. doi: 10.1080/0886022X.2019.1710535

Table 5.

Genotype frequencies of polymorphisms of EGF gene in kidney transplant patients with and without acute rejection episodes.

SNP Genotype Non-AR AR Models OR (95% CI) p Value
n (%) n (%)
rs11568835 G/G 175 (61.6%) 47 (74.6%) Codominant1 0.64 (0.34–1.20) .16
  A/G 93 (32.8%) 16 (25.4%) Codominant2 0.00 (0.00–NA) .047
  A/A 16 (5.6%) 0 (0%) Dominant 0.52 (0.28–0.97) .034
        Recessive 0.00 (0.00–NA) .0076
        Log-additive 0.50 (0.28–0.88) .0099
rs11568943 G/G 181 (63.7%) 39 (61.9%) Codominant1 1.02 (0.56–1.85) .95
  A/G 91 (32%) 20 (31.8%) Codominant2 1.55 (0.47–5.05) .47
  A/A 12 (4.2%) 4 (6.3%) Dominant 1.10 (0.62–1.94) .75
        Recessive 1.53 (0.47–4.95) .5
        Log-additive 1.13 (0.71–1.80) .6
rs2237051 A/A 140 (49.3%) 29 (46%) Codominant1 1.11 (0.63–1.99) .72
  A/G 117 (41.2%) 27 (42.9%) Codominant2 1.25 (0.50–3.15) .63
  G/G 27 (9.5%) 7 (11.1%) Dominant 1.08 (0.62–1.87) .8
        Recessive 1.20 (0.49–2.93) .69
        Log-additive 1.08 (0.72–1.64) .7
rs11569017 A/A 178 (62.7%) 38 (60.3%) Codominant1 1.03 (0.57–1.85) .94
  T/A 96 (33.8%) 21 (33.3%) Codominant2 1.87 (0.56–6.30) .31
  T/T 10 (3.5%) 4 (6.3%) Dominant 1.15 (0.65–2.02) .63
        Recessive 2.02 (0.60–6.78) .28
        Log-additive 1.21 (0.76–1.95) .43
rs3756261 A/A 180 (63.6%) 37 (58.7%) Codominant1 1.19 (0.66–2.14) .56
  A/G 90 (31.8%) 22 (34.9%) Codominant2 1.50 (0.46–4.85) .50
  G/G 13 (4.6%) 4 (6.3%) Dominant 1.26 (0.72–2.22) .42
        Recessive 1.43 (0.45–4.60) .56
        Log-additive 1.23 (0.78–1.94) .37

EGF: epidermal growth factor; AR: acute rejection.