Table 2. Country and study features description—developed countries.

Author	Home country	Study type	Length of data collection	Number of ICUs	Type of ICU	Number of Patients
Abosaif et al, 2005	England	Retrospective	24	1	Mixed	247
Bagshaw et al, 2005	Canada	Prospective	36	3	Mixed	5,693
Chawla et al, 2005	USA	Prospective	8	1	Mixed	194
Ostermann et al, 2005	England and Germany	Retrospective	110	22	Mixed	41,972
Ahlstrom et al, 2006	Finland	Prospective	11	2	Mixed	658
Herrera-Gutiérrez et al, 2006	Spain	Prospective	8	43	Mixed	15,714
Hoste, 2006	USA	Retrospective	12	7	Mixed	5,383
Bagshaw et al, 2007	Australia	Prospective	120	20	Mixed	91,254
Cruz et al, 2007	Italy	Prospective	3	19	Mixed	2,164
Eachempati et al, 2007	USA	Prospective	108	1	Mixed	41,972
Ostermann et al, 2007	England and Germany	Retrospective	120	11	Surgery	8,505
Bagshaw et al, 2008	Australia	Retrospective	60	57	Trauma	124,088
Bagshaw et al, 2008	Australia	Retrospective	60	57	Mixed	120,123
Barrantes et al, 2008	USA	Retrospective	12	1	Mixed	471
Lopes et al, 2008	Portugal	Retrospective	36	1	Mixed	662
Ostermann et al, 2008	England and Germany	Retrospective	123	22	Mixed	23,303
Abelha et al, 2009	Portugal	Retrospective	24	1	Mixed	1,166
Andrikos et al, 2009	Italy and Greece	Prospective	4	22	Mixed	1,076
Cartin-Ceba et al, 2009	USA	Retrospective	42	3	Mixed	11,644
Costantini et al, 2009	USA	Retrospective	36	1	Surgery	571
Joannidis et al, 2009	Austria and Portugal	Prospective	. . .	303	Mixed	16,784
Thakar et al, 2009	USA	Retrospective	60	191	Mixed	325,395
Aldawood et al, 2010	Saudi Arabia	Retrospective	72	1	Mixed	7,173
Cruz et al, 2010	USA	Prospective	6	1	Mixed	301
Elseviers et al, 2010	Belgium	Prospective	35	9	Mixed	1,303
Park et al, 2010	Korea	Retrospective	6	1	Mixed	378
Clec'h et al, 2011	France	Retrospective	149	13	Mixed	8,639
Darmon et al, 2011	France	Prospective	5	3	Mixed	203
Garzotto et al, 2011	Italy	Prospective	7	10	Mixed	576
Macedo et al, 2011	USA	Prospective	2	1	Mixed	75
Macedo et al, 2011	USA	Prospective	. . .	1	Mixed	317
Mandelbaum et al, 2011	USA	Retrospective	72	7	Mixed	14,524
Medve et al, 2011	Hungary	Prospective	2	7	Mixed	459
Ostermann et al, 2011	England and Germany	Retrospective	123	22	Mixed	22,303
Piccini et al, 2011	Italy	Prospective	7	10	Mixed	576
Prowle et al, 2011	Australia, Canada, Japan, USA, Germany, Italy	Prospective	1	7	Mixed	239
Clark et al, 2012	Canada	Prospective	11	11	Mixed	119
Han et al, 2012	Korea	Retrospective	57	1	Mixed	1625
Medve et al, 2012	Hungary	Prospective	. . .	1	Surgery	265
Odutayo et al, 2012	Canada	Prospective	12	5	Mixed	603
Shashaty et al, 2012	USA	Retrospective	45	1	Trauma	400
Sigurdsson et al, 2012	Iceland	Retrospective	12	2	Mixed	1012
Vaara et al, 2012	Finland	Retrospective	23	9	Mixed	30,380
Wohlauer et al, 2012	USA	Prospective	192	1	Surgery	2,158
Allegretti et al, 2013	USA	Retrospective	44	1	Mixed	863
Alsultan et al, 2013	Saudi Arabia	Prospective	36	2	Mixed	2,574
Fuchs et al, 2013	USA	Retrospective	80	1	Mixed	12,339
Legrand et al, 2013	France	Retrospective	48	1	Surgery	137
Nisula et al, 2013	Finland	Prospective	6	10	Mixed	1568
Poukkanen et al, 2013	Finland	Prospective	5	1	Infectious diseases	423
Poukkanen et al, 2013	Finland	Prospective	5	1	Infectious diseases	918
Doi et al, 2014	Japan	Prospective	5	1	Mixed	339
Han et al, 2014	Korea	Retrospective	72	1	Mixed	1,883
Linder et al, 2014	Canada	Prospective	108	1	Mixed	1,844
Shinjo et al, 2014	Japan	Retrospective	60	1	Mixed	2,579
Udy et al, 2014	Australia, Singapore, Hong Kong and Portugal	Prospective	. . .	4	Mixed	281
Bouchard et al, 2015	Various	Prospective	20	9	Mixed	316
Harris et al, 2015	USA	Retrospective	12	1	Surgery	624
Rimes-Stigiare et al, 2015	Sweden	Prospective	72	41	Mixed	97,782
Vanmassenhove et al, 2015	Belgium	Prospective	14	1	Mixed	195