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. 2020 Jan 17;15(1):e0227926. doi: 10.1371/journal.pone.0227926

Fig 6. CNP decrease the number of cristae in melanoma cells.

Fig 6

Melanoma cell were treated with 300 μM CNP for 4 and 24 h or mock-treated (ct). Transmission electron microscopy for cristae quantification was performed as described in the Methods section. CNP significantly decreased the number of cristae in the mitochondrial inner membrane in A375 cells. ANOVA with Dunnet´s post-hoc test was used for the determination of statistical significance among treatment groups. Data are means ± SEM, n = 3. ***, p < 0.0001.