Table 1. Baseline Demographic Data of Seven Cases That Received Combination Therapy With TOF and Intensive GMA for Refractory UC.
| Demography | |
|---|---|
| Male/female (N) | 2/5 |
| Age (years) | 53.3 |
| Mean disease duration (years) | 16.1 |
| Location of lesions (N) | |
| Extensive | 3 |
| Left-sided | 4 |
| Severity (N) | |
| Moderate/severe | 6/1 |
| Concomitant medications for UC (N) | |
| Corticosteroids/budesonide | 6 |
| Mesalamine | 7 |
| Azathioprine | 1 |
| Prior use of anti-TNF-α antibodies (N) | 4 |
| Full Mayo score at baseline | 8.71 |
| Endoscopic sub-score at baseline | 2.4 |
| CRP at baseline (mg/dL) | 0.71 |
The data are presented as means. TOF: tofacitinib; GMA: granulocyte and monocyte adsorptive apheresis; UC: ulcerative colitis; TNF: tumor necrosis factor; CRP: C-reactive protein.