Table 2.
HRs (95% CIs) for incident chronic disease according to two famine exposure subgroups among 92 284 participants
| Non-famine births | Famine births | |
| Ischaemic heart disease | ||
| Cases (cases/PYs (/1000)) | 3475 (4.8) | 1151 (5.9) |
| Model 1 | 1.00 | 1.06 (0.99 to 1.14) |
| Model 2 | 1.00 | 1.07 (1.00 to 1.15) |
| Model 3 | 1.00 | 1.07 (0.99 to 1.14) |
| Major coronary events | ||
| Cases (cases/PYs (/1000)) | 390 (0.5) | 125 (0.6) |
| Model 1 | 1.00 | 1.10 (0.89 to 1.36) |
| Model 2 | 1.00 | 1.12 (0.90 to 1.38) |
| Model 3 | 1.00 | 1.11 (0.90 to 1.38) |
| Cerebrovascular disease | ||
| Cases (cases/PYs (/1000)) | 5579 (7.8) | 1753 (9.0) |
| Model 1 | 1.00 | 1.03 (0.98 to 1.09) |
| Model 2 | 1.00 | 1.04 (0.98 to 1.10) |
| Model 3 | 1.00 | 1.05 (0.99 to 1.11) |
| Ischaemic stroke | ||
| Cases (cases/PYs (/1000)) | 3026 (4.2) | 980 (5.0) |
| Model 1 | 1.00 | 1.04 (0.97 to 1.12) |
| Model 2 | 1.00 | 1.05 (0.97 to 1.13) |
| Model 3 | 1.00 | 1.06 (0.99 to 1.15) |
| Haemorrhagic stroke | ||
| Cases (cases/PYs (/1000)) | 630 (0.9) | 186 (0.9) |
| Model 1 | 1.00 | 1.03 (0.87 to 1.22) |
| Model 2 | 1.00 | 1.05 (0.89 to 1.25) |
| Model 3 | 1.00 | 1.06 (0.89 to 1.25) |
| Cancer | ||
| Cases (cases/PYs (/1000)) | 2431 (3.3) | 680 (3.4) |
| Model 1 | 1.00 | 1.02 (0.93 to 1.11) |
| Model 2 | 1.00 | 1.01 (0.93 to 1.11) |
| Model 3 | 1.00 | 1.01 (0.92 to 1.10) |
| Respiratory system disease | ||
| Cases (cases/PYs (/1000)) | 11 815 (18.4) | 3390 (19.5) |
| Model 1 | 1.00 | 0.96 (0.93 to 1.00) |
| Model 2 | 1.00 | 0.97 (0.93 to 1.01) |
| Model 3 | 1.00 | 0.97 (0.93 to 1.01) |
| COPD | ||
| Cases (cases/PYs (/1000)) | 691 (1.0) | 176 (0.9) |
| Model 1 | 1.00 | 1.05 (0.88 to 1.25) |
| Model 2 | 1.00 | 1.06 (0.89 to 1.26) |
| Model 3 | 1.00 | 1.07 (0.90 to 1.27) |
Model 1 was adjusted for sex (men or women). Model 2 additionally included education (no formal school, primary school, middle school, high school, college, or university or higher), marital status (married, widowed, divorced or separated, or never married), smoking (never smoker, former smoker who had quit for reasons other than illness, current smoker or former smoker who had quit because of illness: 1–14, 15–24, or ≥25 cigarettes or equivalent tobacco per day), alcohol consumption (non-weekly drinker, former weekly drinker, weekly drinker, daily drinker: <15, 15–29, 30–59 or ≥60 g of pure alcohol), physical activity (MET-hours/day), intakes of fruits, vegetables and red meat (day/week; calculated by assigning participants to the midpoint of their consumption category), family history of heart attack, stroke or cancer (presence or absence; only adjusted for in corresponding analysis of specific diseases) and menopausal status (premenopausal, perimenopausal or postmenopausal; for women only); model 3: additionally included body mass index, WHR, and prevalent hypertension and diabetes at baseline (presence or absence).
COPD, chronic obstructive pulmonary disease; MET, metabolic equivalent of task; PYs, person-years; WHR, waist:hip ratio.