Table 3.

Sex-specific HRs (95% CIs) for incident chronic disease according to two famine exposure subgroups

	Men (n=35 953)		Women (n=56 331)		Pinteraction
	Non-famine births	Famine births	Non-famine births	Famine births
No of participants	28 204	7749	44 286	12 045
Ischaemic heart disease					0.388
Cases	1346	439	2129	712
Cases/PYs (/1000)	4.8	5.7	4.8	5.9
HRs (95% CIs)	1.00	1.04 (0.93 to 1.17)	1.00	1.08 (0.99 to 1.18)
Major coronary events					0.832
Cases	263	85	127	40
Cases/PYs (/1000)	0.9	1.1	0.3	0.3
HRs (95% CIs)	1.00	1.09 (0.84 to 1.42)	1.00	1.15 (0.79 to 1.67)
Cerebrovascular disease					0.016
Cases	2157	640	3422	1113
Cases/PYs (/1000)	7.8	8.4	7.8	9.4
HRs (95% CIs)	1.00	1.00 (0.91 to 1.09)	1.00	1.09 (1.01 to 1.17)
Ischaemic stroke					0.136
Cases	1306	405	1720	575
Cases/PYs (/1000)	4.6	5.3	3.8	4.8
HRs (95% CIs)	1.00	1.04 (0.92 to 1.17)	1.00	1.08 (0.98 to 1.20)
Haemorrhagic stroke					0.271
Cases	314	86	316	100
Cases/PYs (/1000)	1.1	1.1	0.7	0.8
HRs (95% CIs)	1.00	0.97 (0.76 to 1.25)	1.00	1.15 (0.91 to 1.45)
Cancer					0.790
Cases	904	250	1527	430
Cases/PYs (/1000)	3.2	3.2	3.4	3.5
HRs (95% CIs)	1.00	1.08 (0.93 to 1.25)	1.00	0.97 (0.87 to 1.09)
Respiratory system disease					0.063
Cases	4195	1273	7620	2117
Cases/PYs (/1000)	16.9	18.7	19.5	20.0
HRs (95% CIs)	1.00	1.00 (0.93 to 1.06)	1.00	0.95 (0.90 to 1.00)
COPD					0.908
Cases	293	76	398	100
Cases/PYs (/1000)	1.1	1.0	0.9	0.8
HRs (95% CIs)	1.00	1.08 (0.83 to 1.41)	1.00	1.06 (0.84 to 1.33)

Multivariable model was adjusted for the same set of covariates as in model 3 of table 2 except for sex.

COPD, chronic obstructive pulmonary disease; PYs, person-years.