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. 2020 Jan 17;82(1):15. doi: 10.1007/s11538-019-00675-0

Fig. 6.

Fig. 6

Summary of the key findings of this paper. If the two phenotypes can coexist, a highly invasive community of cells emerges. Conversely, if TM dominates, tumour invasion comes to a halt as the cells are unable to overcome the stroma. If TA dominates, then a temporarily invasive tumour mass forms in which TM cells find a temporary habitat in the matrix at the tumour edge. Finally, in the case where the two cell types mutually exclude each other’s growth, the cells separate into spatially distinct regions and fail to invade (Colour figure online)