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. 2019 Nov 18;476(1):147–157. doi: 10.1007/s00428-019-02683-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/

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Fig. 1 — Osteoid osteoma and osteoblastoma. a Osteoid osteoma. b Osteoblastoma show identical morphology at haematoxylin and eosin staining, with deposition of woven bone by osteoblast-like tumour cells. c Fluorescence in situ hybridization (FISH) showing FOS rearrangement in osteoblastoma. d Immunohistochemical staining for FOS in osteoblastoma showing nuclear overexpression in the tumour cells. Scale bar is 50 μm