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. 2020 Jan 17;10:556. doi: 10.1038/s41598-020-57486-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Quantitative analysis of individual beta cell distribution in the rat pancreas administrated with crude polysaccharide and rhamnose enriched polysaccharide from G. lithophila. 3D visualization in scatter plot of islet size distribution with beta cells in various size and shape. Circularity represents the roundness of structure (1.0 denotes perfect circle), Feret’s diameter (µm) displays the distance within structure. (a–e) showed the quantification of beta cells in body region of pancreas from group I–V, (f–j) showed the quantification of beta cells in head region of pancreas from group I–V, (k–o)showed the quantification of beta cells in tail region of pancreas from group I–V.